Recent Publications

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PubMedTrending15h

Takotsubo Syndrome Following Emergency Decompression for Acute Cervical Spinal Epidural Hematoma: A Case Report.

Takayama K, Ono Y, Yamada I, Kotani J

BACKGROUND Spinal epidural hematoma is a rare emergency that can occur after minor neck movement and involve the cervical and upper thoracic levels, potentially causing autonomic imbalance. Takotsubo ...

Circulation15h

Cell Type-Specific Targeting of Different Smooth Muscle Cell Populations by Intersectional Genetics.

Wang L, Staps M, Günther S, El Agha E, Bellusci S, Kuenne C, Du J, Schneider A, Braun T

BACKGROUND: The Cre/loxP recombination system is the main tool for cell type-specific lineage tracing and gene targeting. Currently available smooth muscle cell (SMC)-specific Cre mouse lines show...

PubMedTrending15h

Hydroxysafflor Yellow A Attenuates Sepsis-Induced Cardiac Dysfunction by Inhibiting Ferroptosis via Activation of Thioredoxin.

Chen Y, Cai X, Nan W, Peng Z

Ferroptosis is increasingly recognized as a key driver of sepsis-induced cardiac dysfunction. Hydroxysafflor yellow A (HSYA), a bioactive flavonoid, shows cardioprotective properties, but its role in ...

PubMedTrending15h

A Real-World Disproportionality Analysis of Drug-Induced Heart Failure: Integrating FAERS Database and AHA Statement.

Li D, Dong Y, Yao L, Chen X, Li Y, Deng X, Li J, Wang M, Fu D

Heart failure (HF), the advanced stage of diverse cardiac conditions, poses a significant public health challenge. This study analyzes adverse event (AE) signals associated with HF within the FDA Adve...

PubMedTrending1d

Successful Spontaneous Twin Pregnancy Following Bone Marrow Transplant and Gastric Cancer Surgery: A Case Report.

Almuhaisen HKS, AlShubat SA, AlRaqeeb AN, Saeed AlQarni EA

BACKGROUND Pregnancy following bone marrow transplantation (BMT) and treatment for gastric cancer is rare because of gonadotoxic conditioning regimens, major abdominal surgery, and the overall burden ...

PubMedTrending2d

Cardiovascular disease risk across subsectors and occupations in the transportation and storage industry: a national cohort study.

Oh J, Park H, Lee J, Lee J, Yun B, Yoon JH

Cardiovascular disease (CVD) is a major contributor to global morbidity and mortality. While the transportation industry is recognized as high-risk for CVD, variation across subsectors and occupations...

Lancet2d

Contemporary non-invasive imaging for coronary artery disease.

Hunyor I, Wilcox I, O'Sullivan J

PubMedTrending2d

Safety and efficacy of anticoagulation for cerebral amyloid angiopathy patients with high-risk atrial fibrillation.

Chen H, Kakadiya J, Salim HA, Essibayi MA, Adcock A, Yedavalli VS, Dmytriw AA, Colasurdo M, Malhotra A, Gandhi D, Lakhani DA

BACKGROUND: Cerebral amyloid angiopathy (CAA) significantly increases intracranial hemorrhage (ICH) risk and the safety of anticoagulation (AC) among CAA patients with atrial fibrillation (AF) is ...

PubMedTrending2d

A Mathematical Model for Smooth Muscle Cell Phenotype Switching In Atherosclerotic Plaque.

Ndenda JP, Watson MG, Misra A, Myerscough MR

Smooth muscle cells (SMCs) play a fundamental role in the development of atherosclerotic plaques. They ingest lipids in a similar way to monocyte-derived macrophages (MDMs) in the plaque. This can sti...

Lancet2d

Coronary revascularisation before TAVI.

Garot P, Akodad M

Lancet2d

Deferral of percutaneous coronary intervention in patients undergoing transcatheter aortic valve implantation (PRO-TAVI): an investigator-initiated, multicentre, open-label, non-inferiority, randomised controlled trial.

Delewi R, Aarts HM, Broeze GM, Hemelrijk KI, van Ginkel DJ, Versteeg GAA, Grundeken MJ, Claessen BEPM, Tonino PAL, Schotborgh CE, Meuwissen M, van Houwelingen GK, Wykrzykowska JJ, Amoroso G, Vossenberg TN, Vriesendorp PA, van Royen N, Ten Berg JM, Tijssen JGP, Voskuil M

BACKGROUND: Coronary artery disease is common in patients undergoing transcatheter aortic valve implantation (TAVI). We aimed to assess whether deferral of percutaneous coronary intervention (PCI)...

Lancet2d

Aspirin versus clopidogrel for chronic maintenance monotherapy after percutaneous coronary intervention: 10-year follow-up of the HOST-EXAM trial.

Kang J, Park S, Yang HM, Shin ES, Rha SW, Bae JW, Lee NH, Yoon HJ, Cho YH, Kim U, Kim SY, Kim SH, Han JK, Park KW, Kim HS

BACKGROUND: The long-term clinical outcomes of clopidogrel monotherapy versus aspirin monotherapy after percutaneous coronary intervention (PCI) remain uncertain. We conducted a 10-year follow-up ...

PubMedTrending3d

Efficacy and Safety of preoperative Controlling Heart Rate in Patients with Acute Type A Aortic Dissection (ESCORT): protocol for a randomised controlled trial.

Liu G, Wang D, Yang Y, Zhang T, Xie B, Hu J, Wei X, Chen J, Yuan S, Yu C

INTRODUCTION: Aortic dissection (AD) is a life-threatening cardiovascular emergency with a high mortality rate, and acute Stanford Type A AD is the most dangerous form, often requiring surgical in...

PubMedTrending3d

Optimising the emergency-readiness of public access defibrillators across Wales using quality improvement methodology.

Goodfellow S, Hardyman W, Sullivan J, Starling J

Early bystander cardiopulmonary resuscitation and use of automated external defibrillators (AEDs) have been shown to significantly improve survival from out-of-hospital cardiac arrest (OHCA). Public a...

Nat Rev Cardiol3d

Extremes of temperature and cardiovascular mortality.

Nguyen N, Jain U